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John R Gordon Selected Research

CXCR Receptors

1/2017CXCL8 Antagonist Improves Diabetic Nephropathy in Male Mice With Diabetes and Attenuates High Glucose-Induced Mesangial Injury.
3/2015Behavioral alterations in rat offspring following maternal immune activation and ELR-CXC chemokine receptor antagonism during pregnancy: implications for neurodevelopmental psychiatric disorders.
10/2012G31P, an antagonist against CXC chemokine receptors 1 and 2, inhibits growth of human prostate cancer cells in nude mice.

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John R Gordon Research Topics

Disease

17Inflammation (Inflammations)
06/2022 - 01/2004
11Asthma (Bronchial Asthma)
06/2022 - 01/2004
9Neoplasms (Cancer)
11/2018 - 04/2002
8Respiratory Hypersensitivity
06/2022 - 01/2004
5Pneumonia (Pneumonitis)
06/2022 - 12/2005
4Endotoxemia
03/2009 - 12/2005
3Fibrosis (Cirrhosis)
11/2018 - 05/2011
3Neoplasm Metastasis (Metastasis)
08/2015 - 04/2014
2Immune System Diseases (Immune Disorders)
01/2021 - 01/2014
2Schizophrenia (Dementia Praecox)
07/2018 - 03/2015
2Chronic Disease (Chronic Diseases)
07/2017 - 09/2008
2Diarrhea
05/2017 - 01/2006
2Type 2 Diabetes Mellitus (MODY)
01/2017 - 11/2007
2Hepatocellular Carcinoma (Hepatoma)
02/2015 - 04/2014
2Necrosis
04/2013 - 02/2003
2Infections
09/2009 - 11/2007
2Bacterial Infections (Bacterial Infection)
12/2007 - 11/2002
2Wounds and Injuries (Trauma)
05/2002 - 05/2002
1Arthritis (Polyarthritis)
01/2021
1Juvenile Arthritis (Juvenile Idiopathic Arthritis)
01/2021
1Psoriatic Arthritis
01/2021
1Nephritis
11/2018
1Gout
11/2018
1Ulcerative Colitis
07/2018
1Peanut Hypersensitivity (Peanut Allergy)
05/2017
1Food Hypersensitivity (Food Allergy)
05/2017
1Diabetic Nephropathies (Diabetic Nephropathy)
01/2017
1Breast Neoplasms (Breast Cancer)
01/2017
1Insulin Resistance
01/2017
1Ischemic Stroke
10/2015
1Lung Neoplasms (Lung Cancer)
08/2015
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
08/2015
1Mental Disorders (Mental Disorder)
03/2015
1Liver Neoplasms (Liver Cancer)
02/2015
1Acute Kidney Injury (Acute Renal Failure)
02/2015
1Atherosclerosis
01/2013
1Hyperlipidemias (Hyperlipidemia)
01/2013
1Prostatic Neoplasms (Prostate Cancer)
10/2012
1Ischemia
08/2010
1Aspiration Pneumonia
02/2010
1Body Weight (Weight, Body)
02/2010

Drug/Important Bio-Agent (IBA)

14CXC ChemokinesIBA
11/2018 - 11/2002
9CytokinesIBA
06/2022 - 12/2002
9Interleukin-8 (Interleukin 8)IBA
11/2018 - 03/2008
8AllergensIBA
05/2017 - 01/2004
6ChemokinesIBA
08/2015 - 12/2002
4Immunoglobulin G (IgG)IBA
01/2021 - 03/2011
3Proteins (Proteins, Gene)FDA Link
06/2022 - 02/2015
3Immunoglobulin E (IgE)IBA
01/2021 - 08/2013
3Interleukin-10 (Interleukin 10)IBA
01/2021 - 09/2007
3CXCR ReceptorsIBA
01/2017 - 10/2012
3Therapeutic UsesIBA
01/2013 - 12/2005
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2006 - 02/2003
3Peptides (Polypeptides)IBA
03/2005 - 11/2002
2Methacholine Chloride (Methacholine)FDA Link
06/2022 - 01/2004
2Messenger RNA (mRNA)IBA
01/2021 - 08/2015
2Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2017
2LipopolysaccharidesIBA
11/2018 - 10/2006
2Mutant Proteins (Protein, Mutant)IBA
11/2018 - 08/2015
2GTP-Binding Proteins (G-Protein)IBA
11/2018 - 07/2018
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2018 - 10/2012
2ElementsIBA
01/2018 - 11/2002
2OvalbuminIBA
05/2017 - 03/2005
2Transcription Factors (Transcription Factor)IBA
01/2017 - 10/2012
2Cisplatin (Platino)FDA LinkGeneric
02/2015 - 04/2014
2Biological ProductsIBA
01/2013 - 01/2004
2Peptide Hydrolases (Proteases)FDA Link
03/2011 - 03/2005
2leucylarginineIBA
02/2010 - 12/2007
2Chemotactic FactorsIBA
09/2009 - 11/2002
2AntigensIBA
03/2005 - 11/2002
2EnzymesIBA
03/2005 - 05/2002
2Transforming Growth Factors (Transforming Growth Factor)IBA
05/2002 - 05/2002
2Transforming Growth Factor beta1 (TGF beta 1)IBA
05/2002 - 05/2002
1Low Density Lipoprotein Receptor-Related Protein-1 (LDL-Receptor Related Protein)IBA
01/2021
1AntibodiesIBA
01/2021
1Rheumatoid FactorIBA
01/2021
1Interleukin-13IBA
01/2021
1Uric Acid (Urate)IBA
11/2018
1Dextran SulfateIBA
07/2018
1Tretinoin (Retinoic Acid)FDA LinkGeneric
05/2017
1Histone Deacetylase InhibitorsIBA
01/2017
1Metformin (Glucophage)FDA LinkGeneric
01/2017
1ATP-Binding Cassette Transporters (ABC Transporters)IBA
01/2017
1Pharmaceutical PreparationsIBA
01/2017
1Glucose (Dextrose)FDA LinkGeneric
01/2017
1Apoptosis Regulatory ProteinsIBA
08/2015
1Caspase 8 (Caspase-8)IBA
08/2015
1CreatinineIBA
04/2014
1Urea (Carbamide)FDA LinkGeneric
04/2014
1NitrogenIBA
04/2014
1Interleukin-5 (Interleukin 5)IBA
08/2013
1Interleukin-4 (Interleukin 4)IBA
08/2013
1COLD-fXIBA
12/2011
1PlacebosIBA
08/2010
1LipidsIBA
09/2009

Therapy/Procedure

7Therapeutics
01/2021 - 04/2002
2Immunotherapy
05/2017 - 01/2014
2Drug Therapy (Chemotherapy)
01/2017 - 04/2014
1Radiotherapy
05/2011
1Euthanasia (Mercy Killing)
05/2011